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Hydroxyurea-induced acute interstitial pneumonitis in a patient with essential thrombocythemia

Quintás Cardama, Alfonso; Pérez Encinas, Manuel Mateo; González Pérez, Marta Sonia; Bendaña López, Mª Ángeles; Bello López, José Luis
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URI: http://hdl.handle.net/20.500.11940/22701
PMID: 10348150
DOI: 10.1007/s002770050498
ISSN: 0939-5555
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Ann Hematol. 1999 Apr;78(4):187-8 (322.1Kb)
VERSIÓN DEL EDITOR (63.17Kb)
Date issued
1999-04
Journal title
Annals of Hematology
Type of content
Artigo
DeCS
enfermedades pulmonares intersticiales | neumonía | trombocitemia esencial | hidroxiurea
MeSH
Hydroxyurea | Thrombocythemia, Essential | Lung Diseases, Interstitial | Pneumonia
CIE
Otras enfermedades pulmonares intersticiales
Abstract
[EN] Hydroxyurea is a drug widely used to control myeloproliferative disorders, due in part to its relative lack of severe side effects. We present a case of acute interstitial pneumonitis in a patient who was treated with hydroxyurea for essential thrombocythemia. The clinical course suggests that the interstitial pneumonitis was induced by hydroxyurea. This is the first case of hydroxyurea-induced acute interstitial pneumonitis reported in the literature.

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