Effectiveness of rotavirus vaccination in Spain

Martinón Torres, Federico; Bouzón Alejandro, Marta; Redondo Collazo, Lorenzo; Sanchez Lastres, J. M.; Pertega Diaz, Sonia; Seoane Pillado, María Teresa; Martinón Sánchez, José María; Alvarez Garcia, F.; Alvarez Garnelo, E.; Amado Puentes, A.; Andres Andres, A. G.; Ares Alvarez, J.; Baza Vilarino, C.; Boullosa Estevez, M.; Busto Cuinas, M.; Caamano Gonzalez, M.; Carballeira Gonzalez, I.; Carballo Silva Mo, A.; Castellon Gallego, A.; Crespo Suarez, P.; Del Rio Pastoriza, I.; Gonzalez Conde Ma, V.; Fernandez Martinez, N.; Fernandez Perez, M. A.; Garcia Sendon, C.; Kamal Kdamel, M.; Lago Mandado, P.; Lia Taborda, A.; Lopez Del Olmo Mo, C.; Lopez Franco, M.; Lopez Sousa, M.; Martinez Abad, P.; Martinon Torres, N.; Miguelez Diaz, R.; Molinos Norniella, C.; Murias Taboada Mo, C.; Ordonez Alvarez, F. A.; Perez Gomez, E.; Perez Lopez, A.; Portugueses De La Red, M.; Rodriguez De La Rua Fernandez, V.; Rodriguez Suarez, J.; Sampedro Campos, Manuel; Suarez Otero, G.; Torre Rodriguez, I.; Vadillo Gonzalez, F.
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URI: http://hdl.handle.net/20.500.11940/2985
PMID: 21521947
ISSN: 1554-8600
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Date issued
2011
Journal title
Human Vaccines
Type of content
Artigo
MeSH
Female | Humans | Male | Spain | Infant | Infant, Newborn | Hospitalization | Rotavirus Vaccines | Gastroenteritis | Rotavirus Infections | Rotavirus | Vaccination
Abstract
With the aim of determining rotavirus vaccine effectiveness (RVVE) in Spain, from Oct-2008/Jun-2009, 467 consecutive children below 2 years old with acute gastroenteritis (AGE) were recruited using a pediatric research network (ReGALIP-www.regalip.org) that includes primary, emergency and hospital care settings. Of 467 enrolled children, 32.3% were rotavirus positive and 35.0% had received at least one dose of any rotavirus vaccine. RRVE to prevent any episode of rotavirus AGE was 91.5% (95% CI: 83.7%-95.6%). RVVE to prevent hospitalization by rotavirus AGE was 95.6% (85.6-98.6%). No differences in RVVE were found regarding the vaccine used. Rotavirus vaccines have showed an outstanding effectiveness in Spain.