TY - JOUR AU - Ear, J. AU - Dunkel, Y. AU - Mittal, Y. AU - Lim, B. B. C. AU - Liu, L. AU - Holda, M. K. AU - Nitsche, U. AU - Barbazán García, Jorge AU - Goel, A. AU - Janssen, K. P. AU - Aznar, N. AU - Ghosh, P. PY - 2019 SN - 2045-2322 UR - http://hdl.handle.net/20.500.11940/15427 AB - Previously, Aznar et al., showed that Daple/CCDC88C enables Wnt receptors to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein binding and activating (GBA) motif. By doing so, Daple serves two opposing roles;... LA - eng KW - Humans KW - Genes KW - HeLa Cells KW - COS Cells KW - RNA KW - Mice KW - Animals KW - Protein Binding KW - Cohort Studies KW - NIH 3T3 Cells TI - Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors DO - 10.1038/s41598-019-48420-w T2 - Scientific Reports M2 - 12124 KW - CHUS KW - IDIS VL - 9 ER -