TY - JOUR AU - Elez, Elena AU - Pericay, Carles AU - Valladares Ayerbes, Manuel AU - Bando, Inmaculada AU - Safont, Maria Jose AU - Gallego, Javier AU - Gravalos, Cristina AU - Arrivi, Antonio AU - Carrato, Alfredo AU - Conde, Veronica AU - Ortiz, Maria Jose AU - Lopez, Carlos AU - Alonso, Beatriz AU - Ruiz de Mena, Inmaculada AU - Diaz-Rubio, Eduardo AU - Tabernero, Josep AU - Aranda, Enrique PY - 2019 SN - 0007-0920 UR - http://hdl.handle.net/20.500.11940/15918 AB - BACKGROUND: Targeted agents are standard treatment for RAS wild-type metastatic colorectal cancer in the first- and second-line settings. This phase 2 study determined the benefit of targeting the epidermal growth factor receptor (EGFR) with... LA - eng KW - Membrane Proteins KW - Adult KW - Peritoneal Neoplasms KW - Proto-Oncogene Proteins B-raf KW - Middle Aged KW - GTP Phosphohydrolases KW - Adenocarcinoma KW - Lymph Nodes KW - Proto-Oncogene Proteins p21(ras) KW - Survival Rate KW - Drug Eruptions KW - Magnesium KW - Antineoplastic Combined Chemotherapy Protocols KW - Diarrhea KW - Lung Neoplasms KW - Humans KW - Treatment Outcome KW - Asthenia KW - Water-Electrolyte Imbalance KW - Liver Neoplasms KW - Salvage Therapy KW - Aged KW - Colorectal Neoplasms KW - PTEN Phosphohydrolase TI - A phase 2 study of panitumumab with irinotecan as salvage therapy in chemorefractory KRAS exon 2 wild-type metastatic colorectal cancer patients DO - 10.1038/s41416-019-0537-z T2 - BRITISH JOURNAL OF CANCER KW - CHUAC VL - 121 ER -