TY  - JOUR 
AU  - Nogueira Recalde, Uxía
AU  - Lorenzo Gómez, Irene
AU  - BLANCO GARCIA, FRANCISCO JAVIER
AU  - Loza, Maria I
AU  - Grassi, Diego
AU  - Shirinsky, Valery
AU  - Shirinsky, Ivan
AU  - Lotz, Martin
AU  - Robbins, Paul D
AU  - Dominguez, Eduardo
AU  - Cerdeira Caramés, Sara
PY  - 2019
SN  - 2352-3964
UR  - http://hdl.handle.net/20.500.11940/15929
AB  - BACKGROUND: Ageing-related failure of homeostasis mechanisms contributes to articular cartilage degeneration and osteoarthritis (OA), for which disease-modifying treatments are not available. Our objective was to identify molecules to prevent OA by...
LA  - eng
KW  - Apoptosis
KW  - Fenofibrate
KW  - Lipid Metabolism
KW  - Mice
KW  - Chondrocytes
KW  - Animals
KW  - Osteoarthritis
KW  - Interleukin-6
KW  - Therapeutics
KW  - PPAR alpha
KW  - Autophagy
KW  - Aging
KW  - Humans
KW  - Cells
KW  - Cartilage Diseases
KW  - Cartilage
TI  - Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
DO  - 10.1016/j.ebiom.2019.06.049
T2  - EBioMedicine
KW  - CHUAC
KW  - INIBIC
VL  - 45.
ER  -