TY - JOUR AU - Borrero-Palacios, A AU - Cebrian, A AU - Gomez Del Pulgar, M T AU - Garcia-Carbonero, R AU - Garcia-Alfonso, P AU - Aranda, E AU - Elez, E AU - Lopez-Lopez, R AU - Cervantes, A AU - Valladares Ayerbes, Manuel AU - Nadal, C AU - Vieitez, J M AU - Guillen-Ponce, C AU - Rodriguez, J AU - Hernandez, I AU - Garcia, J L AU - Vega-Bravo, R AU - Puime-Otin, A AU - Martinez-Useros, J AU - Del Puerto-Nevado, L AU - Rincon, R AU - Rodriguez-Remirez, M AU - Rojo, F AU - Garcia-Foncillas, J PY - 2019 SN - 2045-2322 UR - http://hdl.handle.net/20.500.11940/15950 AB - Cetuximab is a standard-of-care treatment for RAS wild-type metastatic colorectal cancer (mCRC) but not for those harbor a KRAS mutation since MAPK pathway is constitutively activated. Nevertheless, cetuximab also exerts its effect by its... LA - eng KW - Adult KW - Middle Aged KW - Humans KW - Genes KW - Treatment Outcome KW - Drug Resistance KW - Prospective Studies KW - Proto-Oncogene Proteins p21(ras) KW - Aged KW - Colorectal Neoplasms KW - Antineoplastic Agents TI - Combination of KIR2DS4 and FcgammaRIIa polymorphisms predicts the response to cetuximab in KRAS mutant metastatic colorectal cancer DO - 10.1038/s41598-019-39291-2 T2 - Scientific Reports KW - CHUAC VL - 9 ER -