TY  - JOUR 
AU  - Carobbio, S.
AU  - Hagen, R. M.
AU  - Lelliott, C. J.
AU  - Slawik, M.
AU  - Medina-Gomez, G.
AU  - Tan, C. Y.
AU  - Sicard, A.
AU  - Atherton, H. J.
AU  - Barbarroja, N.
AU  - Bjursell, M.
AU  - Bohlooly-Y, M.
AU  - Virtue, S.
AU  - Tuthill, A.
AU  - Lefai, E.
AU  - Laville, M.
AU  - Wu, T.
AU  - Considine, R. V.
AU  - Vidal, H.
AU  - Langin, D.
AU  - Oresic, M.
AU  - Tinahones, F. J.
AU  - Fernandez-Real, J. M.
AU  - Griffin, J. L.
AU  - Sethi, J. K.
AU  - López Pérez, Miguel A.
AU  - Vidal-Puig, A.
PY  - 2013
SN  - 0012-1797
UR  - http://hdl.handle.net/20.500.11940/2449
AB  - The epidemic of obesity imposes unprecedented challenges on human adipose tissue (WAT) storage capacity that may benefit from adaptive mechanisms to maintain adipocyte functionality. Here, we demonstrate that changes in the regulatory feedback set...
LA  - eng
KW  - 3T3-L1 Cells
KW  - Adaptation, Physiological
KW  - Adipose Tissue, White
KW  - Animals
KW  - Down-Regulation
KW  - Humans
KW  - Insulin Resistance
KW  - Lipid Metabolism
KW  - Membrane Proteins
KW  - Mice
KW  - Mice, Knockout
KW  - Obesity
KW  - Obesity, Morbid
KW  - RNA, Messenger
KW  - Stearoyl-CoA Desaturase
KW  - Sterol Regulatory Element Binding Protein 1
TI  - Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity
DO  - 10.2337/db12-1748
T2  - DIABETES
M2  - 3697
VL  - 62
ER  -