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dc.contributor.authorBugallo-Carrera, C.
dc.contributor.authorFacal Mayo, David
dc.contributor.authorDomínguez-Lenogue, C.
dc.contributor.authorÁlvarez-Vidal, V.
dc.contributor.authorGandoy Crego, Manuel
dc.contributor.authorCaamaño Ponte, José
dc.date.accessioned2025-08-26T10:59:58Z
dc.date.available2025-08-26T10:59:58Z
dc.date.issued2022
dc.identifier.citationBugallo-Carrera C, Facal D, Domínguez-Lenogue C, Álvarez-Vidal V, Gandoy-Crego M, Caamaño-Ponte J. Neuropsychiatric Symptoms after Liver Transplantation in a 65-Year-Old Male Patient. Brain Sciences. 2022;12(12).
dc.identifier.issn2076-3425
dc.identifier.otherhttps://portalcientifico.sergas.gal/documentos/63b996e04386723d2da378e5*
dc.identifier.urihttp://hdl.handle.net/20.500.11940/20779
dc.description.abstractThe development of immunosuppressants has been key for the advancement of solid organ transplant surgery. Specifically, cyclosporine, tacrolimus, or everolimus have significantly increased the survival rate of patients by reducing the risk of a rejection of the transplanted organ and limiting graft-versus-host disease. We report the case of a 65-year-old man who, after undergoing a liver transplantation and receiving an immunosuppressive treatment with cyclosporine and everolimus, presented severe obsessive, psychotic, and behavioral symptoms over the past three years, and describe the pharmacological and non-pharmacological interventions implemented against these symptoms. In this case, the immunosuppressants used have been cyclosporine and, preferably, everolimus. On the other hand, potential adverse reactions to the treatment have been observed, including neuropsychiatric symptoms such as tremor, anxiety, dysthymia, psychosis, and behavioral disorders, which make it necessary to use corrective psychoactive drugs such as benzodiazepines, antidepressants, and antipsychotics, combined with non-pharmacological interventions. A transversal approach, from the medical and psychosocial disciplines, facilitates success in managing neuropsychiatric symptoms after soft organ transplants.en
dc.language.isoeng
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleNeuropsychiatric Symptoms after Liver Transplantation in a 65-Year-Old Male Patient*
dc.typeArticleen
dc.authorsophosBugallo-Carrera, J. C.
dc.authorsophosFacal, D.
dc.authorsophosDomínguez-Lenogue, C.
dc.authorsophosÁlvarez-Vidal, V.
dc.authorsophosGandoy-Crego, M.
dc.authorsophosCaamaño, Ponte
dc.identifier.doi10.3390/brainsci12121721
dc.identifier.sophos63b996e04386723d2da378e5
dc.issue.number12
dc.journal.titleBrain Sciences*
dc.relation.publisherversionhttps://www.mdpi.com/2076-3425/12/12/1721/pdf?version=1671168743;https://mdpi-res.com/d_attachment/brainsci/brainsci-12-01721/article_deploy/brainsci-12-01721.pdf?version=1671168743es
dc.rights.accessRightsopenAccess
dc.subject.keywordIDISes
dc.subject.keywordAS Coruña APes
dc.typefidesArtículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis)es
dc.typesophosArtículo Originales
dc.volume.number12


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