TY - JOUR AU - Alves, J. M. AU - Prado-López, S. AU - Cameselle Teijeiro, Jose Manuel AU - Posada, D. PY - 2019 SN - 2041-1723 UR - http://hdl.handle.net/20.500.11940/15368 AB - How and when tumoral clones start spreading to surrounding and distant tissues is currently unclear. Here we leveraged a model-based evolutionary framework to investigate the demographic and biogeographic history of a colorectal cancer. Our analyses... LA - eng KW - Humans KW - Genetic Heterogeneity KW - Neoplasm Metastasis KW - Disease Progression KW - Colorectal Neoplasms TI - Rapid evolution and biogeographic spread in a colorectal cancer DO - 10.1038/s41467-019-12926-8 T2 - Nature Communications M2 - 5139 KW - CHUS VL - 10 ER -