TY  - JOUR 
AU  - Thomas, R.
AU  - Trapani, D.
AU  - Goodyer-Sait, L.
AU  - Tomkova, M.
AU  - Fernández Rozadilla, Ceres
AU  - Sahnane, N.
AU  - Woolley, C.
AU  - Davis, H.
AU  - Chegwidden, L.
AU  - Kriaucionis, S.
AU  - Maughan, T.
AU  - Leedham, S.
AU  - Palles, C.
AU  - Furlan, D.
AU  - Tomlinson, I.
AU  - Lewis, A.
PY  - 2019
SN  - 2045-2322
UR  - http://hdl.handle.net/20.500.11940/15553
AB  - Expression of the mismatch repair gene MutL homolog 1 (MLH1) is silenced in a clinically important subgroup of sporadic colorectal cancers. These cancers exhibit hypermutability with microsatellite instability (MSI) and differ from...
TI  - The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression
DO  - 10.1038/s41598-019-49952-x
T2  - Scientific Reports
M2  - 13463
KW  - FPGMX
KW  - IDIS
VL  - 9
ER  -