TY - JOUR AU - Franke, F. C. AU - Müller, J. AU - Abal Posada, Miguel AU - Medina, E. D. AU - Nitsche, U. AU - Weidmann, H. AU - Chardonnet, S. AU - Ninio, E. AU - Janssen, K. P. PY - 2019 SN - 2352-345X UR - http://hdl.handle.net/20.500.11940/15765 AB - Background & Aims: The tumor-suppressor sterile alpha motif- and Src-homology 3-domain containing 1 (SASH1) has clinical relevance in colorectal carcinoma and is associated specifically with metachronous metastasis. We sought to identify the molecular... LA - eng KW - CRISPR-Cas Systems KW - Tumor Suppressor Proteins KW - src Homology Domains KW - Neoplasm Invasiveness KW - Neoplasm Metastasis KW - HCT116 Cells KW - Phenotype KW - Signal Transduction KW - Epithelial-Mesenchymal Transition KW - Protein Binding KW - Nuclear Proteins KW - HEK293 Cells KW - Humans KW - Amino Acid Motifs KW - Colorectal Neoplasms TI - The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer DO - 10.1016/j.jcmgh.2018.08.007 T2 - CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY M2 - 33 KW - IDIS VL - 7 ER -