TY - JOUR AU - Heras, Violeta AU - Sangiao Alvarellos, Susana AU - Manfredi-Lozano, Maria AU - Sanchez-Tapia, Maria J AU - Ruiz-Pino, Francisco AU - Roa, Juan AU - Lara-Chica, Maribel AU - Morrugares-Carmona, Rosario AU - Jouy, Nathalie AU - Abreu, Ana P AU - Prevot, Vincent AU - Belsham, Denise AU - Vazquez, Maria J AU - Calzado, Marco A AU - Pinilla, Leonor AU - Gaytan, Francisco AU - Latronico, Ana C AU - Kaiser, Ursula B AU - Castellano, Juan M AU - Tena-Sempere, Manuel PY - 2019 SN - 1544-9173 UR - http://hdl.handle.net/20.500.11940/15896 AB - Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; yet, the molecular underpinnings of this key... LA - eng KW - Sexual Maturation KW - Ubiquitin-Protein Ligases KW - Rats KW - MicroRNAs KW - Cell Line KW - Hypothalamus KW - Animals KW - Gene Expression Regulation KW - Binding Sites KW - Sequence Analysis TI - Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3 DO - PBIOLOGY-D-19-00285 T2 - PLOS BIOLOGY KW - INIBIC VL - 17 ER -