TY  - JOUR 
AU  - Calvete, Oriol
AU  - Garcia-Pavia, Pablo
AU  - Dominguez, Fernando
AU  - Mosteiro, Lluc
AU  - Perez-Cabornero, Lucia
AU  - Cantalapiedra, Diego
AU  - Zorio, Esther
AU  - Ramon Y Cajal, Teresa
AU  - Crespo Leiro, Marisa
AU  - Teule, Alex
AU  - Lazaro, Conxi
AU  - Morente, Manuel M
AU  - Urioste, Miguel
AU  - Benitez, Javier
PY  - 2019
SN  - 2047-9980
UR  - http://hdl.handle.net/20.500.11940/15906
AB  - Background Mutations in the POT1 gene explain abnormally long telomeres and multiple tumors including cardiac angiosarcomas (CAS). However, the link between long telomeres and tumorigenesis is poorly understood. Methods and Results Here, we have...
LA  - eng
KW  - Apoptosis
KW  - Vascular Endothelial Growth Factor Receptor-2
KW  - Signal Transduction
KW  - Cell Cycle Checkpoints
KW  - Tumor Suppressor Protein p53
KW  - DNA Damage
KW  - Hemangiosarcoma
KW  - Immunohistochemistry
KW  - Mutation
KW  - Telomere-Binding Proteins
KW  - DNA-Binding Proteins
KW  - Transcription Factors
KW  - Humans
KW  - Carcinogenesis
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Heart Neoplasms
KW  - Case-Control Studies
TI  - POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas
DO  - 10.1161/JAHA.119.012875
T2  - JOURNAL OF THE AMERICAN HEART ASSOCIATION
KW  - CHUAC
KW  - INIBIC
VL  - 8
ER  -