TY - JOUR AU - Perez-Garcia, Selene AU - Carrion, Mar AU - Villanueva-Romero, Raul AU - Hermida Gómez, Tamara AU - Fernandez Moreno, Mercedes AU - Mellado, Mario AU - BLANCO GARCIA, FRANCISCO JAVIER AU - Juarranz, Yasmina AU - Gomariz, Rosa P PY - 2019 SN - 1582-1838 UR - http://hdl.handle.net/20.500.11940/15942 AB - Failure of therapeutic approaches for the treatment of osteoarthritis (OA) based on the inhibition of metalloproteinases, might be because of their constitutive expression in homeostasis, together with their network complexity. The knowledge of this... LA - eng KW - Wnt Signaling Pathway KW - Humans KW - Fibroblasts KW - Cartilage Oligomeric Matrix Protein KW - Interleukin-1beta KW - Extracellular Matrix KW - Core Binding Factor Alpha 1 Subunit KW - Synovial Membrane KW - Osteoarthritis KW - Fibronectins KW - Aged KW - Cartilage TI - Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast-derived ADAMTS-7 and -12. DO - 10.1111/jcmm.14283 T2 - JOURNAL OF CELLULAR AND MOLECULAR MEDICINE KW - CHUAC KW - INIBIC VL - 23 ER -