TY - JOUR AU - Barrachina, M. N. AU - Martís Sueiro, Aurelio Manuel AU - Izquierdo, I. AU - Hermida-Nogueira, L. AU - Guitián, E. AU - Casanueva Freijo, Felipe AU - Farndale, R. W. AU - Moroi, M. AU - Jung, S. M. AU - Pardo, M. AU - García, Á PY - 2019 SN - 0021-9150 UR - http://hdl.handle.net/20.500.11940/16077 AB - BACKGROUND AND AIMS: Platelets play a fundamental role in the increased atherothrombotic risk related to central obesity since they show hyperactivation and lower sensitivity to antiplatelet therapy in obese patients. The main goal of this study was... LA - eng KW - Adult KW - Platelet Activation KW - Platelet Aggregation KW - Adolescent KW - Obesity KW - Phospholipase C gamma KW - Platelet Membrane Glycoproteins KW - Up-Regulation KW - Body Mass Index KW - Signal Transduction KW - Proteomics KW - Blood Platelets KW - Humans KW - Young Adult KW - Phosphorylation KW - Case-Control Studies TI - GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity DO - 10.1016/j.atherosclerosis.2018.12.023 T2 - ATHEROSCLEROSIS KW - CHUS KW - IDIS VL - 281 ER -