TY - GEN AU - Varela Eirín, Marta AU - Carpintero Fernández, Paula AU - Sánchez Temprano, Agustín AU - Varela Vázquez, Adrian AU - Paíno, Carlos Luis AU - Casado-Díaz, Antonio AU - Continente, Alfonso Calañas AU - Mato, Virginia AU - Fonseca Capdevila, Eduardo AU - Kandouz, Mustapha AU - Blanco, Alfonso AU - Caeiro Rey, José Ramón AU - Mayan Santos, María Dolores PY - 2020 SN - 1945-4589 UR - http://hdl.handle.net/20.500.11940/16211 AB - Articular cartilage and synovial tissue from patients with osteoarthritis (OA) show an overactivity of connexin43 (Cx43) and accumulation of senescent cells associated with disrupted tissue regeneration and disease progression. The aim of this study... KW - Polyphenols KW - Cellular Microenvironment KW - Osteogenesis KW - Iridoid Glucosides KW - Connexin 43 KW - Chondrocytes KW - Signal Transduction KW - NF-kappa B KW - Osteoarthritis KW - Fruit KW - Nuclear Proteins KW - Iridoids KW - Cell Differentiation KW - Cell Line KW - Chondrogenesis KW - Humans KW - Antirheumatic Agents KW - Collagen Type II KW - Regeneration KW - Aged KW - Cartilage TI - Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis DO - 10.18632/aging.103801 KW - CHUS KW - INIBIC VL - 12 ER -