TY - GEN AU - Araújo, Nuna AU - Viegas, Carla S B AU - Zubía, Eva AU - Magalhaes Silva, Joana Cristina AU - Ramos, Acácio AU - Carvalho, Maria M AU - Cruz, Henrique AU - Sousa, João Paulo AU - BLANCO GARCIA, FRANCISCO JAVIER AU - Vermeer, Cees AU - Simes, Dina C PY - 2020 SN - 1660-3397 UR - http://hdl.handle.net/20.500.11940/16223 AB - Osteoarthritis (OA) remains a prevalent chronic disease without effective prevention and treatment. Amentadione (YP), a meroditerpenoid purified from the alga Cystoseira usneoides, has demonstrated anti-inflammatory activity. Here, we investigated the... KW - Gene Expression KW - Anti-Inflammatory Agents KW - Chondrocytes KW - Diterpenes KW - Coculture Techniques KW - Osteoarthritis KW - Cyanobacteria KW - Humans KW - Antirheumatic Agents KW - Durapatite KW - Primary Cell Culture KW - Interleukin-1beta KW - Inflammation KW - Cartilage TI - Amentadione from the Alga Cystoseira usneoides as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model DO - 10.3390/md18120624 KW - CHUAC KW - INIBIC VL - 18 ER -