TY - GEN AU - Palau, P. AU - Seller, J. AU - Dominguez, E. AU - Gómez Otero, María Inés AU - Ramon, J. M. AU - Sastre, C. AU - de la Espriella, R. AU - Santas, E. AU - Minana, G. AU - Chorro, F. J. AU - González Juanatey, José Ramón AU - Nunez, J. PY - 2020 SN - 0160-9289 UR - http://hdl.handle.net/20.500.11940/16677 AB - BACKGROUND: The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is complex and multifactorial. Chronotropic incompetence (ChI) has emerged as a crucial pathophysiological mechanism. Beta-blockers, drugs with negative... KW - Ventricular Function KW - Humans KW - Adrenergic beta-Antagonists KW - Multicenter Studies as Topic KW - Prospective Studies KW - Benzodiazepines KW - Stroke Volume KW - Randomized Controlled Trials as Topic KW - Research Design KW - Heart Failure TI - Beta-blockers withdrawal in patients with heart failure with preserved ejection fraction and chronotropic incompetence: Effect on functional capacity rationale and study design of a prospective, randomized, controlled trial (The Preserve-HR trial) DO - 10.1002/clc.23345 KW - CHUS VL - 43 ER -