TY - JOUR AU - Rodríguez-Soler, María AU - Pérez-Carbonell, Lucía AU - Guarinos, Carla AU - Zapater, Pedro AU - Castillejo, Adela AU - Barbera, Victor M. AU - Juarez, Miriam AU - Bessa, Xavier Xicola, Rosa M. AU - Clofent, Juan AU - Bujanda, Luis AU - Balaguer, Francesc AU - Rene, Josep-Maria AU - De Castro Parga, María Luisa AU - Marin-Gabriel, Jose C. AU - Lanas, Angel AU - Cubiella Fernández, Joaquín AU - Nicolas-Perez, David AU - Brea Fernández, Alejandro AU - Castellvi-Bel, Sergi AU - Alenda, Cristina AU - Ruiz Ponte, Clara AU - Carracedo Álvarez, Angel AU - Castells, Antoni AU - Andreu, Montserrat AU - Llor, Xavier AU - Soto, Jose L. AU - Paya, Artemio AU - Jover, Rodrigo PY - 2013 SN - 0016-5085 UR - http://hdl.handle.net/20.500.11940/1928 AB - BACKGROUND & AIMS: Colorectal cancers (CRCs) with microsatellite instability (MSI) and a mismatch repair (MMR) immunohistochemical deficit without hypermethylation of the MLH1 promoter are likely to be caused by Lynch syndrome. Some patients with... LA - eng KW - Adaptor Proteins, Signal Transducing KW - Adult KW - Aged KW - Aged, 80 and over KW - Colorectal Neoplasms, Hereditary Nonpolyposis KW - DNA Mismatch Repair KW - DNA Repair KW - DNA, Neoplasm KW - Female KW - Germ-Line Mutation KW - Humans KW - Immunohistochemistry KW - Incidence KW - Male KW - Microsatellite Instability KW - Middle Aged KW - MutL Protein Homolog 1 KW - Nuclear Proteins KW - Population Surveillance KW - Risk Factors KW - Spain TI - Risk of Cancer in Cases of Suspected Lynch Syndrome Without Germline Mutation DO - 10.1053/j.gastro.2013.01.044 T2 - Gastroenterology VL - 144 ER -