TY  - GEN 
AU  - Val, C.
AU  - Rodríguez-Garciá, C.
AU  - Prieto-Diáz, R.
AU  - Crespo, A.
AU  - Azuaje, J.
AU  - Carbajales, C.
AU  - Majellaro, M.
AU  - Diáz-Holguín, A.
AU  - Brea Floriani, José Manuel
AU  - Loza García, María Isabel
AU  - Gioé-Gallo, C.
AU  - Contino, M.
AU  - Stefanachi, A.
AU  - Garciá-Mera, X.
AU  - Estévez, J.C.
AU  - Gutiérrez-De-Terán, H.
AU  - Sotelo, E.
PY  - 2022
SN  - 1520-4804
UR  - http://hdl.handle.net/20.500.11940/20417
AB  - We herein document a large collection of 108 2-amino-4,6-disubstituted-pyrimidine derivatives as potent, structurally simple, and highly selective A1AR ligands. The most attractive ligands were confirmed as antagonists of the canonical cyclic...
LA  - eng
TI  - Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1Antagonists
DO  - 10.1021/acs.jmedchem.1c01636
KW  - AS Santiago
KW  - IDIS
VL  - 65
ER  -