TY - GEN AU - Sáenz de Urturi, D. AU - Buqué, X. AU - Porteiro Couto, Begoña AU - Folgueira, C. AU - Mora, A. AU - Delgado, T.C. AU - Prieto-Fernández, E. AU - Olaizola, P. AU - Gómez-Santos, B. AU - Apodaka-Biguri, M. AU - González-Romero, F. AU - Nieva-Zuluaga, A. AU - Ruiz de Gauna, M. AU - Goikoetxea-Usandizaga, N. AU - García-Rodríguez, J.L. AU - Gutierrez de Juan, V. AU - Aurrekoetxea, I. AU - Montalvo-Romeral, V. AU - Novoa, E.M. AU - Martín-Guerrero, I. AU - Varela-Rey, M. AU - Bhanot, S. AU - Lee, R. AU - Banales, J.M. AU - Syn, W.-K. AU - Sabio, G. AU - Martínez-Chantar, M.L. AU - Nogueiras, R. [4192646] AU - Aspichueta, P. PY - 2022 SN - 2041-1723 UR - http://hdl.handle.net/20.500.11940/20434 AB - Altered methionine metabolism is associated with weight gain in obesity. The methionine adenosyltransferase (MAT), catalyzing the first reaction of the methionine cycle, plays an important role regulating lipid metabolism. However, its role in... LA - eng TI - Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis DO - 10.1038/s41467-022-28749-z KW - AS Santiago KW - IDIS VL - 13 ER -