TY  - GEN 
AU  - Astolfi, A.
AU  - Milano, F.
AU  - Palazzotti, D.
AU  - Brea Floriani, José Manuel
AU  - Pismataro, M.C.
AU  - Morlando, M.
AU  - Tabarrini, O.
AU  - Loza García, María Isabel
AU  - Massari, S.
AU  - Martelli, M.P.
AU  - Barreca, M.L.
PY  - 2022
SN  - 1999-4923
UR  - http://hdl.handle.net/20.500.11940/20718
AB  - Acute myeloid leukemia (AML) is a heterogeneous hematopoietic malignancy whose prognosis is globally poor. In more than 60% of AML patients, the PI3K/AKTs/mTOR signaling pathway is aberrantly activated because of oncogenic driver alterations and...
LA  - eng
TI  - From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia
DO  - 10.3390/pharmaceutics14112295
KW  - AS Santiago
KW  - IDIS
VL  - 14
ER  -