TY - JOUR AU - Romero Picó, Amparo AU - Vázquez Villar, María Jesús AU - González Touceda, David AU - Folgueira Cobos, Cintia AU - Skibicka, K. P. AU - Alvarez-Crespo, M. AU - Van Gestel, M. A. AU - Velásquez Raimundo, Douglas A. AU - Schwarzer, C. AU - Herzog, H. AU - López Pérez, Miguel A. AU - Adan, R. A. AU - Dickson, S. L. AU - Diéguez González, Carlos AU - Nogueiras Pozo, Rubén PY - 2013 SN - 0893-133X UR - http://hdl.handle.net/20.500.11940/2087 AB - The opioid system is well recognized as an important regulator of appetite and energy balance. We now hypothesized that the hypothalamic opioid system might modulate the orexigenic effect of ghrelin. Using pharmacological and gene silencing... LA - eng KW - Agouti-Related Protein KW - Animals KW - Arcuate Nucleus of Hypothalamus KW - Conditioning, Operant KW - Drug Interactions KW - Eating KW - Enkephalins KW - Gene Silencing KW - Ghrelin KW - Infusions, Intraventricular KW - Intracellular Signaling Peptides and Proteins KW - Male KW - Microinjections KW - Narcotic Antagonists KW - Neuropeptide Y/metabolism KW - Neuropeptides KW - Orexins KW - Protein Precursors KW - Rats KW - Receptors, Ghrelin KW - Receptors, Opioid, kappa KW - Reinforcement Schedule KW - Signal Transduction KW - Ventral Tegmental Area TI - Hypothalamic κ-opioid receptor modulates the orexigenic effect of ghrelin DO - 10.1038/npp.2013.28 T2 - NEUROPSYCHOPHARMACOLOGY M2 - 1296 VL - 38 ER -