TY - JOUR AU - Tur, C. AU - Carbonell-Mirabent, P. AU - Cobo-Calvo, A. AU - Otero-Romero, S. AU - Arrambide, G. AU - Midaglia ., Luciana Soledad AU - Castilló, J. AU - Vidal-Jordana, A. AU - Rodríguez-Acevedo, B. AU - Zabalza, A. AU - Galán, I. AU - Nos, C. AU - Salerno, A. AU - Auger, C. AU - Pareto, D. AU - Comabella, M. AU - Río, J. AU - Sastre-Garriga, J. AU - Rovira, À. AU - Tintoré, M. AU - Montalban, X. PY - 2023 SN - 2168-6157 UR - http://hdl.handle.net/20.500.11940/21121 AB - Importance: Progression independent of relapse activity (PIRA) is the main event responsible for irreversible disability accumulation in relapsing multiple sclerosis (MS). Objective: To investigate clinical and neuroimaging predictors of PIRA at the... LA - eng KW - Humans KW - Female KW - Adult KW - Multiple Sclerosis KW - Cohort Studies KW - Chronic Disease KW - Prognosis KW - Recurrence TI - Association of Early Progression Independent of Relapse Activity with Long-term Disability after a First Demyelinating Event in Multiple Sclerosis DO - 10.1001/jamaneurol.2022.4655 T2 - JAMA Neurology M2 - 151 KW - AS Vigo KW - CHUVI VL - 80 ER -