TY - JOUR AU - Intranuovo, F. AU - Brunetti, L. AU - Delre, P. AU - Mangiatordi, G.F. AU - Stefanachi, A. AU - Laghezza, A. AU - Niso, M. AU - Leonetti, F. AU - Loiodice, F. AU - Ligresti, A. AU - Kostrzewa, M. AU - Brea Floriani, José Manuel AU - Loza García, María Isabel AU - Sotelo, E. AU - Saviano, M. AU - Colabufo, N.A. AU - Riganti, C. AU - Abate, C. AU - Contino, M. PY - 2023 SN - 1520-4804 UR - http://hdl.handle.net/20.500.11940/21397 AB - Cannabinoid type 2 receptor (CB2R), belonging to the endocannabinoid system, is overexpressed in pathologies characterized by inflammation, and its activation counteracts inflammatory states. Fatty acid amide hydrolase (FAAH) is an enzyme responsible... LA - eng KW - Cannabinoids KW - Endocannabinoids KW - Receptor, Cannabinoid, CB2 KW - Molecular Docking Simulation KW - Benzamides KW - Anti-Inflammatory Agents KW - Amidohydrolases KW - Cannabinoid Receptor Agonists KW - Receptor, Cannabinoid, CB1 TI - Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase DO - 10.1021/acs.jmedchem.2c01084 T2 - Journal of Medicinal Chemistry M2 - 235 KW - AS Santiago KW - IDIS VL - 66 ER -