TY - JOUR AU - Abatti, L.E. AU - Lado-Fernández, P. AU - Huynh, L. AU - Collado Rodríguez, Manuel AU - Hoffman, M.M. AU - Mitchell, J.A. PY - 2023 SN - 1362-4962 UR - http://hdl.handle.net/20.500.11940/21508 AB - Enhancer reprogramming has been proposed as a key source of transcriptional dysregulation during tumorigenesis, but the molecular mechanisms underlying this process remain unclear. Here, we identify an enhancer cluster required for normal development... LA - eng KW - Animals KW - Humans KW - Mice KW - Adenocarcinoma of Lung KW - Carcinogenesis KW - Chromatin KW - Enhancer Elements, Genetic KW - Epigenesis, Genetic KW - Homozygote KW - Lung Neoplasms KW - Sequence Deletion KW - SOXB1 Transcription Factors TI - Epigenetic reprogramming of a distal developmental enhancer cluster drives SOX2 overexpression in breast and lung adenocarcinoma DO - 10.1093/nar/gkad734 T2 - Nucleic acids research M2 - 10109 KW - AS Santiago KW - CHUS VL - 51 ER -