TY - JOUR AU - Vera-Zambrano, A. AU - Lago-Docampo, M. AU - Gallego, N. AU - Franco-Gonzalez, J.F. AU - Morales-Cano, D. AU - Cruz-Utrilla, A. AU - Villegas-Esguevillas, M. AU - Fernández-Malavé, E. AU - Escribano-Subías, P. AU - Tenorio-Castaño, J.A. AU - Perez-Vizcaino, F. AU - Valverde Pérez, Diana AU - González, T. AU - Cogolludo, A. PY - 2023 SN - 1535-4989 UR - http://hdl.handle.net/20.500.11940/21790 AB - Reduced expression and/or activity of Kv1.5 channels (encoded by KCNA5) is a common hallmark in human or experimental pulmonary arterial hypertension (PAH). Likewise, genetic variants in KCNA5 have been found in patients with PAH, but their functional... LA - eng KW - Humans KW - Pulmonary Arterial Hypertension KW - HEK293 Cells KW - Hypertension, Pulmonary KW - Kv1.5 Potassium Channel KW - Familial Primary Pulmonary Hypertension KW - Pulmonary Artery TI - Novel Loss-of-Function KCNA5 Variants in Pulmonary Arterial Hypertension DO - 10.1165/rcmb.2022-0245oc T2 - American Journal of Respiratory Cell and Molecular Biology M2 - 147 VL - 69 ER -