TY - JOUR AU - Wang, Yu-Hung AU - Wei, Chao-Hung AU - Lin, Chien-Chin AU - Gurnari, Carmelo AU - Awada, Hussein AU - Benajiba, Lina AU - Daltro de Oliveira, Rafael AU - Soret-Dulphy, Juliette AU - Cassinat, Bruno AU - Zucenka, Andrius AU - Mosquera Orgueira, Adrián AU - Yuan, Chang-Tsu AU - Lee, Sze-Hwei AU - Yao, Chi-Yuan AU - Gurashi, Kristian AU - Hou, Hsin-An AU - Batta, Kiran AU - Pérez Encinas, Manuel Mateo AU - Chou, Wen-Chien AU - Maciejewski, Jaroslaw P AU - Wiseman, Daniel H AU - Kiladjian, Jean-Jacques AU - Tien, Hwei-Fang PY - 2025 UR - http://hdl.handle.net/20.500.11940/22278 AB - [EN] In addition to high-molecular risk (HMR) mutations (ASXL1, EZH2, SRSF2, IDH, and U2AF1Q157), lower JAK2V617F variant allele frequencies (VAF) have been demonstrated to be associated with poor prognosis of myelofibrosis (MF) patients.... LA - eng KW - Prognosis KW - Mutation KW - Primary Myelofibrosis KW - High-Throughput Nucleotide Sequencing KW - Myeloproliferative Disorders KW - Gene Frequency KW - Janus Kinase 2 KW - Survival Rate TI - Synergistic effect of concurrent high molecular risk mutations and lower JAK2 mutant variant allele frequencies on prognosis in patients with myelofibrosis-insights from a multicenter study DO - 10.1038/s41375-024-02422-4 T2 - Leukemia M2 - 144 KW - CHUS KW - IDIS VL - 39 ER -