TY - JOUR AU - Abdulkader Nallib, Ihab AU - Cameselle Teijeiro, Jose Manuel AU - Forteza Vila, Jerónimo PY - 2005 SN - 0309-0167 UR - http://hdl.handle.net/20.500.11940/22323 AB - Gastrointestinal stromal tumors (GISTs) are a distinct tumor type driven by activating mutations in c-kit (detected via CD117 immunohistochemistry) or, less commonly, PDGFRA, leading to constitutive kinase activation that promotes tumor growth.... LA - eng KW - Ependymoma KW - Imatinib Mesylate KW - Benzamides KW - Gastrointestinal Stromal Tumors KW - Humans KW - Antineoplastic Agents KW - Middle Aged KW - Jordan KW - Male KW - Pyrimidines KW - Northern Ireland KW - Neoplasm Metastasis KW - Piperazines KW - Immunohistochemistry KW - Proto-Oncogene Proteins c-kit KW - Treatment Outcome KW - Tyrosine TI - Pathological changes related to Imatinib treatment in a patient with a metastatic gastrointestinal stromal tumour. DO - 10.1111/j.1365-2559.2005.02014.x T2 - Histopathology M2 - 470 KW - CHUS VL - 46 ER -