TY  - JOUR 
AU  - Leiro Fernández, Virginia
AU  - Fernández Villar, José Alberto
AU  - Valverde, Diana
AU  - Constenla Caramés, Lucia
AU  - Vázquez Gallardo, Eladio Rafael
AU  - Piñeiro Amigo, Luis
AU  - González Quintela, Arturo
PY  - 2008
SN  - 1478-3223
UR  - http://hdl.handle.net/20.500.11940/22341
AB  - Genetic variations in enzymes of isoniazid metabolism confer an increased risk for antituberculosis drug-induced hepatotoxicity in Asian populations. The present study was aimed at investigating the possible association of antituberculosis...
LA  - eng
KW  - Genetic Predisposition to Disease
KW  - Genotype
KW  - Antitubercular Agents
KW  - Case-Control Studies
KW  - Rifampin
KW  - Adult
KW  - Aspartate Aminotransferases
KW  - Isoniazid
KW  - Drug Therapy
KW  - Pyrazinamide
KW  - Alanine Transaminase
KW  - Homozygote
KW  - Bilirubin
KW  - Glutathione Transferase
KW  - Male
KW  - Prospective Studies
KW  - Mutation
KW  - Digitalis
KW  - Female
KW  - Risk Factors
KW  - Population
TI  - Influence of glutathione S-transferase M1 and T1 homozygous null mutations on the risk of antituberculosis drug-induced hepatotoxicity in a Caucasian population.
DO  - 10.1111/j.1478-3231.2008.01700.x
T2  - Liver international : official journal of the International Association for the Study of the Liver
M2  - 835
KW  - CHUVI
KW  - IISGS
KW  - CHUS
VL  - 28
ER  -