TY - JOUR AU - Mosquera Orgueira, Adrián AU - Bao Pérez, Laura AU - Mosquera Torre, Alicia AU - Peleteiro Raindo, Andrés AU - Cid López, Miguel AU - Díaz Arias, José AU - Ferreiro Ferro, Roi AU - Antelo Rodríguez, Beatriz AU - González Pérez, Marta Sonia AU - Albors Ferreiro, Manuel AU - Alonso Vence, Natalia AU - Pérez Encinas, Manuel Mateo AU - Bello López, José Luis AU - Martinelli, Giovanni AU - Cerchione, Claudio PY - 2020 UR - http://hdl.handle.net/20.500.11940/22862 AB - [EN] Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene arise in 25-30% of all acute myeloid leukemia (AML) patients. These mutations lead to constitutive activation of the protein product and are divided in two broad types: internal tandem... LA - eng KW - Mutation KW - Leukemia, Myeloid, Acute KW - fms-Like Tyrosine Kinase 3 KW - Antineoplastic Agents KW - Protein Kinase Inhibitors KW - Concurrent Review TI - FLT3 inhibitors in the treatment of acute myeloid leukemia: current status and future perspectives DO - 10.23736/S0026-4806.20.06989-X T2 - Minerva Medica M2 - 427 KW - IDIS KW - CHUS KW - Inhibidor FLT3 VL - 111 ER -