TY - JOUR AU - Contreras-Ruiz, L. AU - Zorzi, G. K. AU - Hileeto, D. AU - López-García, A. AU - Calonge, M. AU - Seijo Rey, Begoña AU - Sánchez Bardanca, Alejandro AU - Diebold, Y. PY - 2013 SN - 0969-7128 UR - http://hdl.handle.net/20.500.11940/3473 AB - MUC5AC is a glycoprotein with gel-forming properties, whose altered expression has been implicated in the pathogenesis of dry eye disease. The aim of our study was to achieve an efficient in vivo transfection of MUC5AC, restore its normal levels in an... LA - eng KW - Animals KW - Conjunctiva KW - Cornea KW - Disease Models, Animal KW - Dry Eye Syndromes KW - Gene Expression KW - Gene Transfer Techniques KW - Goblet Cells KW - Humans KW - Inflammation KW - Mice KW - Mucin 5AC KW - Nanomedicine KW - Nanoparticles KW - Transfection TI - A nanomedicine to treat ocular surface inflammation: Performance on an experimental dry eye murine model DO - 10.1038/gt.2012.56 T2 - GENE THERAPY M2 - 467 VL - 20 ER -