TY - JOUR AU - Porteiro, B. AU - Díaz-Ruíz, A. AU - Martínez, G. AU - Senra, A. AU - Vidal, A. AU - Serrano, M. AU - Gualillo ., Oreste AU - López, M. AU - Malagón, M. M. AU - Diéguez, C. AU - Nogueiras, R. PY - 2013 SN - 0013-7227 UR - http://hdl.handle.net/20.500.11940/3698 AB - Ghrelin, a stomach-derived peptide, stimulates feeding behavior and adiposity. For its orexigenic action, ghrelin triggers a central SIRT1/p53/AMPK pathway. The tumor suppressor p53 also plays an important role in white adipose tissue (WAT), where it... LA - eng KW - Adipogenesis KW - Adipose Tissue, White KW - Adiposity KW - Animals KW - Crosses, Genetic KW - Enzyme Induction KW - Female KW - Gene Expression Profiling KW - Ghrelin KW - Injections, Intraperitoneal KW - Lipogenesis KW - Liver KW - Male KW - Mice KW - Mice, 129 Strain KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Obesity KW - Tissue Culture Techniques KW - Triglycerides KW - Tumor Suppressor Protein p53 KW - Weight Gain TI - Ghrelin requires p53 to stimulate lipid storage in fat and liver DO - 10.1210/en.2013-1176 T2 - Endocrinology M2 - 3671 VL - 154 ER -