TY  - JOUR 
AU  - Rios García, Marcos
AU  - Foretz, M.
AU  - Viollet, B.
AU  - Prieto González, Angel
AU  - Fraga Rodríguez, Máximo Francisco
AU  - Costoya Puente, José Antonio
AU  - Señarís Rodríguez, Rosa Mª
PY  - 2013
SN  - 0008-5472
UR  - http://hdl.handle.net/20.500.11940/3716
AB  - 5'-AMP-activated protein kinase (AMPK) is an energy sensor that controls cell metabolism, and it has been related to apoptosis and cell-cycle arrest. Although its role in metabolic homeostasis is well documented, its function in cancer is much less...
LA  - eng
KW  - AMP-Activated Protein Kinases
KW  - Animals
KW  - Astrocytes
KW  - Astrocytoma
KW  - Cell Line, Tumor
KW  - Cell Nucleus
KW  - Cell Proliferation
KW  - Cell Transformation, Neoplastic
KW  - Disease Models, Animal
KW  - Enzyme Activation
KW  - Gene Expression
KW  - Glioblastoma
KW  - Humans
KW  - Mice
KW  - Protein Transport
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Pyrazoles
KW  - Pyrimidines
KW  - Xenograft Model Antitumor Assays
TI  - AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors
DO  - 10.1158/0008-5472.CAN-12-0861
T2  - CANCER RESEARCH
M2  - 2628
VL  - 73
ER  -