TY - JOUR AU - Barnett, G. C. AU - Thompson, D. AU - Fachal Vilar, Laura AU - Kerns, S. AU - Talbot, C. AU - Elliott, R. M. AU - Dorling, L. AU - Coles, C. E. AU - Dearnaley, D. P. AU - Rosenstein, B. S. AU - Vega Gliemmo, Ana AU - Symonds, P. AU - Yarnold, J. AU - Baynes, C. AU - Michailidou, K. AU - Dennis, J. AU - Tyrer, J. P. AU - Wilkinson, J. S. AU - Gómez Caamaño, Antonio AU - Tanteles, G. A. AU - Platte, R. AU - Mayes, R. AU - Conroy, D. AU - Maranian, M. AU - Luccarini, C. AU - Gulliford, S. L. AU - Sydes, M. R. AU - Hall, E. AU - Haviland, J. AU - Misra, V. AU - Titley, J. AU - Bentzen, S. M. AU - Pharoah, P. D. AU - Burnet, N. G. AU - Dunning, A. M. AU - West, C. M. PY - 2014 SN - 0167-8140 UR - http://hdl.handle.net/20.500.11940/4504 AB - BACKGROUND AND PURPOSE: This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy. MATERIALS AND METHODS: A genome wide association study was performed in 1850 patients from... LA - eng KW - Breast Neoplasms KW - Dose-Response Relationship, Radiation KW - Female KW - Gene Frequency KW - Genetic Predisposition to Disease KW - Genetic Variation KW - Genome-Wide Association Study KW - Genotype KW - Humans KW - Male KW - Polymorphism, Single Nucleotide KW - Prospective Studies KW - Prostatic Neoplasms KW - Radiation Injuries KW - Radiotherapy, Adjuvant KW - Radiotherapy, Intensity-Modulated KW - Adverse effects KW - Genetics KW - Genome-wide association scan KW - Late toxicity KW - Radiotherapy TI - A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity DO - 10.1016/j.radonc.2014.02.012 T2 - RADIOTHERAPY AND ONCOLOGY M2 - 178 VL - 111 ER -