TY  - JOUR 
AU  - Ortolano, Saida
AU  - Vieitez González, Irene
AU  - Agis Balboa, Roberto Carlos
AU  - Spuch Calvar, Carlos
PY  - 2014
SN  - 1756-6606
UR  - http://hdl.handle.net/20.500.11940/5740
AB  - BACKGROUND: Lafora disease is an autosomal recessive form of progressive myoclonic epilepsy caused by defects in the EPM2A and EPM2B genes. Primary symptoms of the pathology include seizures, ataxia, myoclonus, and progressive development of severe...
LA  - eng
KW  - Actins
KW  - Aging|Animals
KW  - Caspase 3
KW  - Cell Count
KW  - Cell Nucleus
KW  - Cerebral Cortex
KW  - Dendrites
KW  - Dual-Specificity Phosphatases
KW  - GABAergic Neurons
KW  - Inclusion Bodies
KW  - Lafora Disease
KW  - Lysosomes
KW  - Mice
KW  - Nerve Growth Factors
KW  - Protein Transport
KW  - Proteolysis
KW  - Subcellular Fractions
KW  - Synapses
KW  - Tumor Suppressor Protein p53
TI  - Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease
DO  - 10.1186/1756-6606-7-7
T2  - Molecular brain
M2  - 7
KW  - laforina
KW  - neurotrofina
VL  - 7
ER  -