TY - JOUR AU - Tomlinson, Ian P.M. AU - Carvajal-Carmona, Luis G. AU - Dobbins, Sara E. AU - Tenesa, Albert AU - Jones, Angela M. AU - Howarth, Kimberley AU - Palles, Claire AU - Broderick, Peter AU - Jaeger, Emma E. M. AU - Farrington, Susan AU - Lewis, Annabelle AU - Prendergast, James G. D. AU - Pittman, Alan M. AU - Theodoratou, Evropi AU - Olver, Bianca AU - Walker, Marion AU - Penegar, Steven AU - Barclay, Ella AU - Whiffin, Nicola AU - Martin, Lynn AU - Ballereau, Stephane AU - Lloyd, Amy AU - Gorman, Maggie AU - Lubbe, Steven AU - Howie, Bryan AU - Marchini, Jonathan AU - Ruiz Ponte, Clara AU - Fernández Rozadilla, Ceres AU - Castells, Antoni AU - Carracedo Álvarez, Angel AU - Castellvi-Bel, Sergi AU - Duggan, David AU - Conti, David AU - Baptiste, Jean AU - Campbell, Harry AU - Sieber, Oliver AU - Lipton, Lara AU - Gibbs, Peter AU - Martin, Nicholas G. AU - Montgomery, Grant W. AU - Young, Joanne AU - Baird, Paul N. AU - Gallinger, Steven AU - Newcomb, Polly AU - Hopper, John AU - Jenkins, Mark A. AU - Aaltonen, Lauri A. AU - Kerr, David J. AU - Cheadle, Jeremy AU - Pharoah, Paul AU - Casey, Graham AU - Houlston, Richard S. AU - Dunlop, Malcolm G. PY - 2011 SN - 1553-7390 UR - http://hdl.handle.net/20.500.11940/5825 AB - Genome-wide association studies (GWAS) have identified 14 tagging single nucleotide polymorphisms (tagSNPs) that are associated with the risk of colorectal cancer (CRC), and several of these tagSNPs are near bone morphogenetic protein (BMP) pathway... LA - eng KW - Bone Morphogenetic Protein 2 KW - Bone Morphogenetic Protein 4 KW - Case-Control Studies KW - Colorectal Neoplasms KW - Gene Frequency KW - Genetic Predisposition to Disease KW - Genetic Variation KW - Genome-Wide Association Study KW - Intercellular Signaling Peptides and Proteins KW - Polymorphism, Single Nucleotide TI - Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer DO - 10.1371/journal.pgen.1002105 T2 - PLoS Genetics VL - 7 ER -