TY - JOUR AU - Vilas, J. M. AU - Ferreiros, A. AU - Carneiro, C. AU - Morey, L. AU - Silva-alvarez, S. D. AU - Fernandes, T. AU - Abad, M. AU - Croce, L. D. AU - Garcia-Caballero, T. AU - Serrano, M. AU - Rivas, C. AU - Vidal, A. AU - Collado, M.Vilas Martínez, Jessica María AU - Ferreirós López, Alba AU - Carneiro Freire, Carmen AU - Morey, Lluis AU - Da Silva Álvarez, Sabela AU - Fernandes, Tania AU - Abad, María AU - Di Croce, Luciano AU - García Caballero, Tomás AU - Serrano, Manuel AU - Rivas, Carmen AU - Vidal, Anxo AU - Collado Rodríguez, Manuel PY - 2015 SN - 1949-2553 UR - http://hdl.handle.net/20.500.11940/8041 AB - Cellular reprogramming to iPSCs has uncovered unsuspected links between tumor suppressors and pluripotency factors. Using this system, it was possible to identify tumor suppressor p27 as a repressor of Sox2 during differentiation. This led to the... LA - eng KW - Animals KW - Cellular Reprogramming KW - Epigenesis, Genetic KW - Gene Expression Regulation, Developmental KW - Gene Expression Regulation, Neoplastic KW - Genotype KW - HEK293 Cells KW - Humans KW - Induced Pluripotent Stem Cells KW - Mice, 129 Strain KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Neoplastic Stem Cells KW - Phenotype KW - Pituitary Neoplasms KW - RNA Interference KW - Retinoblastoma Protein KW - Retinoblastoma-Like Protein p107 KW - Retinoblastoma-Like Protein p130 KW - SOXB1 Transcription Factors KW - Transcription, Genetic KW - Transfection KW - Tumor Suppressor Protein p53 TI - Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins DO - 10.18632/oncotarget.2996 T2 - Oncotarget M2 - 2992 VL - 6 ER -