TY  - JOUR 
AU  - De La Fuente Freire, María
AU  - Jones, M. C.
AU  - Santander-Ortega, M. J.
AU  - Mirenska, A.
AU  - Marimuthu, P.
AU  - Uchegbu, I.
AU  - Schätzlein, A
PY  - 2015
SN  - 1549-9634
UR  - http://hdl.handle.net/20.500.11940/8181
AB  - UNLABELLED: Gemcitabine is currently the standard therapy for pancreatic cancer. However, growing concerns over gemcitabine resistance mean that new combinatory therapies are required to prevent loss of efficacy with prolonged treatment. Here, we...
LA  - eng
KW  - Apoptosis
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Deoxycytidine
KW  - Drug Resistance, Neoplasm
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Pancreatic Neoplasms
KW  - Polypropylenes
KW  - RNA Interference
KW  - Repressor Proteins
KW  - Ubiquitin-Protein Ligases
KW  - Dendrimer
KW  - Dendriplex
KW  - Itch
KW  - Pancreatic Cancer
KW  - Polypropylenimine
KW  - p73
KW  - shRNA
KW  - siRNA
TI  - A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer
DO  - 10.1016/j.nano.2014.09.010
T2  - Nanomedicine-Nanotechnology Biology and Medicine
M2  - 369
VL  - 11
ER  -