TY - JOUR AU - Díaz-Ruiz, A. AU - Guzmán-Ruiz, R. AU - Moreno, N. R. AU - García-Rios, A. AU - Delgado-Casado, N. AU - Membrives, A. AU - Túnez, I. AU - El Bekay, R. AU - Fernández-Real, J. M. AU - Tovar Carro, Sulay AU - Diéguez González, Carlos AU - Tinahones, F. J. AU - Vázquez-Martínez, R. AU - López-Miranda, J. AU - Malagón, M PY - 2015 SN - 1523-0864 UR - http://hdl.handle.net/20.500.11940/8185 AB - AIMS: Obesity is characterized by a low-grade systemic inflammatory state and adipose tissue (AT) dysfunction, which predispose individuals to the development of insulin resistance (IR) and metabolic disease. However, a subset of obese individuals,... LA - eng KW - 3T3-L1 Cells KW - Adipocytes KW - Adult KW - Animals KW - Disease Models, Animal KW - Endoplasmic Reticulum Stress KW - Female KW - Gene Expression Regulation KW - Humans KW - Insulin Resistance KW - Male KW - Mice KW - Obesity, Metabolically Benign KW - Omentum KW - Oxidative Stress KW - Palmitic Acid KW - Proteasome Endopeptidase Complex KW - Subcutaneous Fat KW - Unfolded Protein Response TI - Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity DO - 10.1089/ars.2014.5939 T2 - ANTIOXIDANTS & REDOX SIGNALING M2 - 597 VL - 23 ER -