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dc.contributor.authorZapata Cachafeiro, Maruxa
dc.contributor.authorPiñeiro Lamas, María
dc.contributor.authorGuinovart, María C
dc.contributor.authorLOPEZ VAZQUEZ, PAULA 
dc.contributor.authorVázquez Lago, Juan Manuel 
dc.contributor.authorFigueiras Guzmán, Adolfo
dc.date.accessioned2019-11-21T11:55:41Z
dc.date.available2019-11-21T11:55:41Z
dc.date.issued2019
dc.identifier.issn0305-7453
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337896/es
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/?term=30395222es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/12604
dc.description.abstractOBJECTIVES: Excessive and inappropriate use of antibiotics increases antimicrobial resistance. The aim of this study was to determine the magnitude and determinants of antibiotic dispensing without prescription in Spain by the simulated patient technique. METHODS: A cross-sectional study was conducted with all the pharmacies in a region of north-west Spain (n = 977), between December 2016 and January 2017. Four actors visited the pharmacies simulating a respiratory infection. Four incremental levels of pressure were used to obtain an antibiotic. The education and sex of the person who was dispensing and the area where the pharmacy was located were recorded. The effect of these independent variables on the dispensing of an antibiotic without prescription (1 = yes, 0 = no) was modelled by logistic regression. RESULTS: An antibiotic was obtained in 18.83% (95% CI = 16.5%-21.41%) of the visits. The area influenced the dispensing of antibiotics without a medical prescription, with a greater likelihood of dispensing in rural (OR = 1.79; 95% CI = 1.20-2.68) or semi-rural (OR = 1.66; 95% CI = 1.13-2.44) areas than in urban areas. No association was found with the sex or the training of the person who dispensed the antibiotic. In the pharmacies in urban areas, a lower level of pressure was needed to obtain the antibiotic. CONCLUSIONS: This study shows that one-fifth of the pharmacies still dispense antibiotics without prescription, especially under patient pressure. A rural setting has been identified as a risk factor for dispensing without prescription, so it must be taken into account for future interventions.es
dc.description.sponsorshipFondo de Investigación Sanitariaes
dc.description.sponsorshipInstituto de Salud Carlos IIIes
dc.language.isoenges
dc.relation.isreferencedbyhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337896/es
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshPregnancy*
dc.subject.meshPreventive Medicine*
dc.subject.meshDrug Resistance, Bacterial*
dc.subject.meshPharmacy*
dc.subject.meshSex*
dc.subject.meshAzithromycin*
dc.subject.meshAnti-Bacterial Agents*
dc.titleMagnitude and determinants of antibiotic dispensing without prescription in Spain: a simulated patient studyes
dc.typeArtigoes
dc.bbddEmbase*
dc.bbddWOK*
dc.identifier.doi10.1093/jac/dky440
dc.identifier.essn1460-2091
dc.identifier.pmid30395222
dc.issue.number2es
dc.journal.titleJournal of Antimicrobial Chemotherapyes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Epidemioloxíaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS)es
dc.page.initial511es
dc.page.final514es
dc.relation.projectIDISCIII/Fondo de Investigación Sanitaria/PI15/00844es
dc.relation.publisherversionhttps://academic.oup.com/jac/article/74/2/511/5161208es
dc.rights.accessRightsopenAccesses
dc.subject.decsfarmacia*
dc.subject.decsacitromicina*
dc.subject.decssexo*
dc.subject.decsmedicina preventiva*
dc.subject.decsembarazo*
dc.subject.decsantibacterianos*
dc.subject.decsfarmacorresistencia bacteriana*
dc.subject.keywordAntibióticoses
dc.subject.keywordDispensación de antibióticoses
dc.typefidesArtigo Científico (inclue Orixinal, Orixinal breve, Revisión Sistemática e Meta-análisis)es
dc.typesophosArtículo Originales
dc.volume.number74es


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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