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EUS-guided tissue acquisition in the study of the adrenal glands: Results of a nationwide multicenter study
dc.contributor.author | Martin-Cardona, A. | |
dc.contributor.author | Fernandez-Esparrach, G. | |
dc.contributor.author | Subtil, J. C. | |
dc.contributor.author | IGLESIAS GARCIA, JULIO | |
dc.contributor.author | Garcia-Guix, M. | |
dc.contributor.author | Barturen Barroso, A. | |
dc.contributor.author | Gimeno-Garcia, A. Z. | |
dc.contributor.author | Esteban, J. M. | |
dc.contributor.author | Pardo Balteiro, A. | |
dc.contributor.author | Velasco-Guardado, A. | |
dc.contributor.author | Vazquez-Sequeiros, E. | |
dc.contributor.author | Loras, C. | |
dc.contributor.author | Martinez-Moreno, B. | |
dc.contributor.author | Castellot, A. | |
dc.contributor.author | Huertas, C. | |
dc.contributor.author | Martinez-Lapiedra, M. | |
dc.contributor.author | Sanchez-Yague, A. | |
dc.contributor.author | Teran, A. | |
dc.contributor.author | Morales-Alvarado, V. J. | |
dc.contributor.author | Betes, M. | |
dc.contributor.author | DE LA IGLESIA GARCIA, DANIEL | |
dc.contributor.author | Sánchez-Montes, C. | |
dc.contributor.author | Lozano, M. D. | |
dc.contributor.author | Lariño Noia, José | |
dc.contributor.author | Gines, A. | |
dc.contributor.author | Tebe, C. | |
dc.contributor.author | Gornals, J. B. | |
dc.date.accessioned | 2021-10-14T07:33:35Z | |
dc.date.available | 2021-10-14T07:33:35Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1932-6203 | |
dc.identifier.other | https://www.ncbi.nlm.nih.gov/pubmed/31170163 | |
dc.identifier.other | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553722/pdf/pone.0216658.pdf | |
dc.identifier.uri | http://hdl.handle.net/20.500.11940/15500 | |
dc.description.abstract | BACKGROUND: There are limited data about the role of endoscopic ultrasound-guided tissue acquisition (EUS-TA), by fine needle aspiration (EUS-FNA) or biopsy (EUS-FNB), in the evaluation of the adrenal glands (AG). The primary aim was to assess the diagnostic yield and safety. The secondary aims were the malignancy predictors, and to create a predictive model of malignancy. METHODS: This was a retrospective nationwide study involving all Spanish hospitals experienced in EUS-TA of AGs. Inclusion period was from April-2003 to April-2016. Inclusion criteria: all consecutive cases that underwent EUS-TA of AGs. EUS and cytopathology findings were evaluated. Statistical analyses: diagnostic accuracy of echoendoscopist's suspicion using cytology by EUS-TA, as gold standard; multivariate logistic regression model to predict tumor malignancy. RESULTS: A total of 204 EUS-TA of AGs were evaluated. Primary tumor locations were lung70%, others19%, and unknown11%. AG samples were adequate for cytological diagnosis in 91%, and confirmed malignancy in 60%. Diagnostic accuracy of the endosonographer's suspicion was 68%. The most common technique was: a 22-G (65%) and cytological needle (75%) with suction-syringe (66%). No serious adverse events were described. The variables most associated with malignancy were size>30mm (OR2.27; 95%CI, 1.16-4.05), heterogeneous echo-pattern (OR2.11; 95%CI, 1.1-3.9), variegated AG shape (OR2.46; 95%CI, 1-6.24), and endosonographer suspicion (OR17.46; 95%CI, 6.2-58.5). The best variables for a predictive multivariate logistic model of malignancy were age, sex, echo-pattern, and AG-shape. CONCLUSIONS: EUS-TA of the AGs is a safe, minimally invasive procedure, allowing an excellent diagnostic yield. These results suggest the possibility of developing a pre-EUS procedure predictive malignancy model. | |
dc.rights | Atribución 4.0 Internacional | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | EUS-guided tissue acquisition in the study of the adrenal glands: Results of a nationwide multicenter study | |
dc.type | Artigo | es |
dc.contributor.authorcorp | Spanish Group for EUS-Guided TA in the adrenal gland | |
dc.authorsophos | Iglesias García, Julio | |
dc.authorsophos | Lariño Noia, José | |
dc.authorsophos | De La Iglesia García, Daniel | |
dc.identifier.doi | 10.1371/journal.pone.0216658 | |
dc.identifier.pmid | 31170163 | |
dc.identifier.sophos | 30856 | |
dc.issue.number | 6 | |
dc.journal.title | PLoS One | |
dc.organization | Servizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Dixestivo | |
dc.page.initial | e0216658 | es |
dc.rights.accessRights | openAccess | |
dc.subject.keyword | CHUS | |
dc.typefides | Artículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis) | |
dc.typesophos | Artículo Original | |
dc.volume.number | 14 |