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dc.contributor.authorVeiga Álvarez, Ernesto
dc.contributor.authorTreviño Castellano, Mercedes 
dc.contributor.authorRomay Bello, Ana Belén
dc.contributor.authorNAVARRO DE LA CRUZ, DANIEL 
dc.contributor.authorTRASTOY PENA, ROCIO 
dc.contributor.authorMacía Cortiñas, Manuel 
dc.date.accessioned2021-10-14T12:59:19Z
dc.date.available2021-10-14T12:59:19Z
dc.date.issued2019
dc.identifier.issn0214-3429
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/31271277
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719643/pdf/revespquimioter-32-327.pdf
dc.identifier.urihttp://hdl.handle.net/20.500.11940/15561
dc.description.abstractOBJECTIVE: Several studies have reported greater success of fertilisation by ART in couples who were not infected by Ureaplasma. Increased semen quality and better results have also been observed in couples who were treated with antibiotics to eradicate the infection. The aim of this study was to determine the prevalence of genital mycoplasmas in urine samples from male partners enrolled in the Assisted Reproduction Program (ARP) in our healthcare area so that, positive cases can be treated prior to the use of ART in order to increase the quality of semen, improve the embryo implantation rates and minimize the risk of adverse effects during pregnancy. METHODS: This study included couples enrolled in the ARP during 2016. Mycoplasma detection was made using real-time PCR. In positive cases, both members of the couple were treated with antibiotics until eradication of the microorganism. The antibiotics used were: azithromycin, doxycycline, levofloxacin, moxifloxacin, and clindamycin. RESULTS: Of the 205 men studied, 33 were positive: Ureaplasma urealyticum 15.1%, Mycoplasma hominis 3.9%. Eradication treatment with azithromycin failed in 50% compared to 10.2% for doxycycline. Of the 5 cases treated with levofloxacin, only 2 achieved elimination of U. urealyticum. CONCLUSIONS: We consider that genital mycoplasma routine screening could be useful in order to increase the quality of semen which could simplify the in vitro fertilisation procedures and raise the success rate of embryo implantation and pregnancy, especially when fast, sensitive and specific technics as real time PCR are used.
dc.titlePrevalencia de micoplasmas genitales y respuesta al tratamiento de descolonización en pacientes de reproducción humana asistida
dc.typeArtigoes
dc.authorsophosTreviño Castellano, Mercedes
dc.authorsophosNavarro de la Cruz, Daniel
dc.authorsophosMacía Cortiñas, Manuel
dc.authorsophosRomay Bello, Ana Belén
dc.authorsophosTrastoy Pena, Rocio
dc.authorsophosVeiga Álvarez, Ernesto
dc.identifier.pmid31271277
dc.identifier.sophos31025
dc.issue.number4
dc.journal.titleRevista Espanola de Quimioterapia
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Análise clínicos
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Microbioloxía
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Xinecoloxía e Obstetricia
dc.page.initial327es
dc.page.final332es
dc.subject.keywordCHUS
dc.typefidesArtículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis)
dc.typesophosArtículo Original
dc.volume.number32


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