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dc.contributor.authorGarcia-Dominguez, Jose M.
dc.contributor.authorMaurino, Jorge
dc.contributor.authorMartinez-Gines, Maria L.
dc.contributor.authorCarmona, Olga
dc.contributor.authorCaminero, Ana B.
dc.contributor.authorMedrano, Nicolas
dc.contributor.authorRuiz-Beato, Elena
dc.contributor.authorAres, Adrian
dc.contributor.authorArnal, Carmen
dc.contributor.authorCaminero, Ana B.
dc.contributor.authorCarcelen, Maria
dc.contributor.authorEguia, Pablo
dc.contributor.authordel Carmen Fernandez, Maria
dc.contributor.authorGinestal, Ricardo
dc.contributor.authorLacruz, Laura
dc.contributor.authorLlaneza González, Miguel Ángel 
dc.contributor.authorLopez de Silanes, Carlos
dc.contributor.authorMartin, Gisela
dc.contributor.authorNavarro, Laura
dc.contributor.authorRomero, Beatriz
dc.contributor.authorSeral, Maria
dc.contributor.authorSolar, Myriam
dc.date.accessioned2021-12-10T09:00:07Z
dc.date.available2021-12-10T09:00:07Z
dc.date.issued2019
dc.identifier.issn1471-2458
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528334/pdf/12889_2019_Article_6907.pdfes
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/31109317es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/15805
dc.description.abstractBACKGROUND: In multiple sclerosis (MS), half of affected people are unemployed within 10 years of diagnosis. The aim of this study was to assess the economic impact of MS in adult subjects with relapsing-remitting MS (RRMS) and primary progressive MS (PPMS). METHODS: A multicenter, non-interventional, cross-sectional study was conducted. The Expanded Disability Status Scale (EDSS) and the 23-item Multiple Sclerosis Work Difficulties Questionnaire (MSWDQ-23) were used to assess disability and work performance, respectively. Only indirect costs were considered using the human capital method, including work costs. Professional support costs and informal caregivers' costs were also estimated. RESULTS: A total of 199 subjects were studied (mean age: 43.9 +/- 10.5 years, 60.8% female, 86.4% with RRMS). Median EDSS score was 2.0 (interquartile range: 1.0-3.5) and median MSWDQ-23 total score was 31.5 (15.2, 50.0). The number of employed subjects decreased after MS diagnosis from 70.6 to 47.2%, and the number of retired people increased (23.6%). Mean age of retirement was 43.6 +/- 10.5 years. Ten percent of the population had sick leaves (absenteeism was seen in 90.9% of the student population and 30.9% of the employed population). Professional support in their daily life activities was needed in 28.1% of subjects. Costs for sick leave, work absenteeism, premature retirement and premature work disability/pensioner were euro416.6 +/- 2030.2, euro763.4 +/- 3161.8, euro5810.1 +/- 13,159.0 and euro1816.8 +/- 9630.7, respectively. Costs for professional support and informal caregiving activities were euro1026.93 +/- 4622.0 and euro1328.72, respectively. CONCLUSIONS: MS is responsible for a substantial economic burden due to indirect and informal care costs, even in a population with low physical disability.en
dc.language.isoenges
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshCost of Illness *
dc.subject.meshAdult *
dc.subject.meshMiddle Aged *
dc.subject.meshHumans *
dc.subject.meshAbsenteeism *
dc.subject.meshCross-Sectional Studies *
dc.subject.meshRetirement *
dc.subject.meshMultiple Sclerosis *
dc.titleEconomic burden of multiple sclerosis in a population with low physical disabilityen
dc.typeArtigoes
dc.authorsophosGarcia-Dominguez, Jose M.
dc.authorsophosMaurino, Jorge
dc.authorsophosMartinez-Gines, Maria L.
dc.authorsophosCarmona, Olga
dc.authorsophosCaminero, Ana B.
dc.authorsophosMedrano, Nicolas
dc.authorsophosRuiz-Beato, Elena
dc.authorsophosAres, Adrian
dc.authorsophosArnal, Carmen
dc.authorsophosCaminero, Ana B.
dc.authorsophosCarcelen, Maria
dc.authorsophosEguia, Pablo
dc.authorsophosdel Carmen Fernandez, Maria
dc.authorsophosGinestal, Ricardo
dc.authorsophosLacruz, Laura
dc.authorsophosLlaneza, Miguel
dc.authorsophosLopez de Silanes, Carlos
dc.authorsophosMartin, Gisela
dc.authorsophosNavarro, Laura
dc.authorsophosRomero, Beatriz
dc.authorsophosSeral, Maria
dc.authorsophosSolar, Myriam
dc.identifier.doi10.1186/s12889-019-6907-x
dc.identifier.pmid31109317
dc.identifier.sophos32055
dc.issue.number1es
dc.journal.titleBMC PUBLIC HEALTHes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Ferrol – Complexo Hospitalario Universitario de Ferrol::Neuroloxíaes
dc.page.initial609es
dc.rights.accessRightsopenAccesses
dc.subject.decsabsentismo laboral *
dc.subject.decsjubilación *
dc.subject.decsmediana edad *
dc.subject.decshumanos *
dc.subject.decsestudios transversales *
dc.subject.decsadulto *
dc.subject.decsesclerosis múltiple *
dc.subject.decscoste de las enfermedades *
dc.subject.keywordCHUFes
dc.typefidesArtículo Originales
dc.typesophosArtículo Originales
dc.volume.number19es


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