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dc.contributor.authorCAMESELLE GARCIA, SOLEDAD 
dc.contributor.authorPerez, J. L. F.
dc.contributor.authorAreses Manrique, María Carmen 
dc.contributor.authorFernández De Castro, Jesús Daniel
dc.contributor.authorMosquera-Reboredo, J.
dc.contributor.authorGarcía Mata, Jesús 
dc.date.accessioned2022-01-27T10:40:04Z
dc.date.available2022-01-27T10:40:04Z
dc.date.issued2019
dc.identifier.issn2307-8960
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718783/pdf/WJCC-7-2302.pdfes
dc.identifier.urihttp://hdl.handle.net/20.500.11940/15957
dc.description.abstractBACKGROUND: Primary malignant melanoma of the biliary tract (MBT) is a rare condition whose diagnosis requires excluding a primary origin in another location. This paper reviews the most important characteristics of MBT cases published in the literature and reports a new case. The patient reported here is the first case of primary malignant melanoma of the biliary tract with pulmonary metastasis treated with immunotherapy. This patient remains disease-free 36 mo after the treatment of metastatic lung lesions. CASE SUMMARY: A 51-year-old man was admitted to the gastrointestinal department to study obstructive jaundice of a 1 wk clinical course. Magnetic resonance cholangiopancreatography revealed dilatation of the intrahepatic biliary tract and stenosis of the common hepatic duct. Given the suspicion of biliary tract neoplasia, cholecystectomy and resection of the common hepatic duct were performed with hepatic jejunostomy free of complications. Anatomo-pathological diagnosis was melanoma. After intervention, the patient was referred to the Department of Medical Oncology, where a primary origin was excluded in the skin, mucosa, and eyes. This confirmed diagnosis of primary biliary tract melanoma. Computed tomography was performed 12 mo after the procedure revealed several subcentimetric lung nodules. Wedge resection was performed. After confirming the diagnosis of pulmonary metastasis of primary melanoma of the biliary tract, the patient was started on immunotherapy with nivolumab. Tolerance to treatment was excellent. The patient remains disease-free 36 mo after the treatment of metastatic lung lesions. CONCLUSION: The patient reported here is the first case of primary malignant melanoma of the biliary tract with lung metastases successfully treated with immunotherapy.en
dc.language.isoenges
dc.rightsAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.meshImmunotherapy*
dc.subject.meshBiliary Tract*
dc.titlePrimary malignant melanoma of the biliary tract: A case report and literature reviewen
dc.typeArtigoes
dc.identifier.doi10.12998/wjcc.v7.i16.2302
dc.identifier.pmid31531323
dc.identifier.sophos32674
dc.issue.number16es
dc.journal.titleWORLD JOURNAL OF CLINICAL CASESes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Ourense, Verín e O Barco de Valdeorras - Complexo Hospitalario Universitario de Ourensees
dc.page.initial2302es
dc.page.final2308es
dc.rights.accessRightsopenAccesses
dc.subject.decsinmunoterapia*
dc.subject.decssistema biliar*
dc.subject.keywordCHUOes
dc.typefidesArtículo de Revisiónes
dc.typesophosArtículo de Revisiónes
dc.volume.number7es


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