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dc.contributor.authorJuiz Valiña, Paula
dc.contributor.authorOuteiriño Blanco, Elena 
dc.contributor.authorPertega Diaz, Sonia 
dc.contributor.authorVarela Rodriguez, Bárbara María
dc.contributor.authorGarcía Brao, Maria Jesús
dc.contributor.authorMena Del Río, Enrique 
dc.contributor.authorPena Bello, María Lara
dc.contributor.authorCordido Carro, María
dc.contributor.authorSangiao Alvarellos, Susana
dc.contributor.authorCORDIDO CARBALLIDO, FERNANDO 
dc.date.accessioned2022-02-01T12:59:46Z
dc.date.available2022-02-01T12:59:46Z
dc.date.issued2019
dc.identifier.issn2072-6643
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/31137484es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/16053
dc.description.abstractObesity is associated with several endocrine abnormalities, including thyroid dysfunction. The objective of this study was to investigate the effect of weight loss after bariatric surgery on thyroid-stimulating hormone (TSH) levels in euthyroid patients with morbid obesity. We performed an observational study, evaluating patients with morbid obesity submitted to bariatric surgery. We included 129 patients (92 women) and 31 controls (21 women). Clinical, anthropometric, biochemical, and hormonal parameters were evaluated. The primary endpoint was circulating TSH (microU/mL). Fasting TSH levels were higher in the obese group (3.3 +/- 0.2) than in the control group (2.1 +/- 0.2). The mean excessive body mass index (BMI) loss (EBMIL) 12 months after bariatric surgery was 72.7 +/- 2.1%. TSH levels significantly decreased in the obese patients after surgery; 3.3 +/- 0.2 vs. 2.1 +/- 0.2 before and 12 months after surgery, respectively. Free thyroxine (T4) (ng/dL) levels significantly decreased in the obese patients after surgery; 1.47 +/- 0.02 vs. 1.12 +/- 0.02 before and 12 months after surgery, respectively. TSH decreased significantly over time, and the decrement was associated with the EBMIL. In euthyroid patients with morbid obesity, weight loss induced by bariatric surgery promotes a significant decline of the increased TSH levels. This decrement of TSH is progressive over time after surgery and significantly associated with excess BMI loss.en
dc.language.isoenges
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshWeight Loss *
dc.subject.meshBariatric Surgery *
dc.subject.meshAdult *
dc.subject.meshThyroid Gland *
dc.subject.meshMiddle Aged *
dc.subject.meshHumans *
dc.subject.meshTreatment Outcome *
dc.subject.meshTime Factors *
dc.subject.meshObesity *
dc.subject.meshBody Mass Index *
dc.subject.meshThyrotropin *
dc.subject.meshRetrospective Studies *
dc.titleEffect of weight loss after bariatric surgery on thyroid-stimulating hormone levels in euthyroid patients with morbid obesityen
dc.typeArtigoes
dc.identifier.doi10.3390/nu11051121
dc.identifier.pmid31137484
dc.identifier.sophos34002
dc.issue.number5es
dc.journal.titleNutrientses
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de A Coruña - Complexo Hospitalario Universitario de A Coruña:: ::Cirurxía Xeral e dixestivaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de A Coruña - Complexo Hospitalario Universitario de A Coruña:: ::Endocrinoloxíaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Biomédica da Coruña (INIBIC)es
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de A Coruña - Complexo Hospitalario Universitario de A Coruña:: ::Epidemioloxíaes
dc.page.initial1121es
dc.relation.publisherversionhttps://res.mdpi.com/d_attachment/nutrients/nutrients-11-01121/article_deploy/nutrients-11-01121-v2.pdfes
dc.rights.accessRightsopenAccesses
dc.subject.decsresultado del tratamiento *
dc.subject.decstirotropina *
dc.subject.decsestudios retrospectivos *
dc.subject.decsglándula tiroides *
dc.subject.decsobesidad *
dc.subject.decsmediana edad *
dc.subject.decspérdida de peso *
dc.subject.decshumanos *
dc.subject.decsfactores de tiempo *
dc.subject.decsadulto *
dc.subject.decsíndice de masa corporal *
dc.subject.decscirugía bariátrica *
dc.subject.keywordCHUACes
dc.subject.keywordINIBICes
dc.typefidesArtículo Originales
dc.typesophosArtículo Originales
dc.volume.number11es


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Atribución 4.0 Internacional
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