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dc.contributor.authorPereiro Brea, Tara
dc.contributor.authorGolpe Gómez, Antonio 
dc.contributor.authorGolpe-Sánchez, Antonio Miguel
dc.contributor.authorValdés Cuadrado, Luis 
dc.contributor.authorMartínez de Alegría Alonso, Anxo 
dc.contributor.authorCarreira Villamor, José Martín 
dc.contributor.authorRuano-Raviña, Alberto
dc.date.accessioned2022-03-08T08:49:57Z
dc.date.available2022-03-08T08:49:57Z
dc.date.issued2020
dc.identifier.issn1198-2241
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/32587645es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/16204
dc.description.abstractIntroduction: Lung cancer is a major health problem. Mediastinal staging performed with the aid of imaging techniques is essential for appropriate disease treatment and prognosis. Accordingly, this study aimed to ascertain the usefulness of positron emission tomography (PET) in mediastinal staging, establish the best maximum standardized uptake value (SUVmax) cutoff point, compare its usefulness to that of computed tomography (CT), and determine the influence of histological tumour subtype. Methods: We conducted a retrospective study across a period of 3 years on 128 patients with suspicion of lung cancer and analyzed their demographic and radiological characteristics using CT and PET to perform the mediastinal examination. Histology was regarded as the gold standard. Results: PET displayed a high sensitivity (95%) and negative predictive value (NPV) (92%), outperforming CT (89% and 85%, respectively). Percentage agreement with histology was also higher (0.207 and 0.241 for CT and PET, respectively; p < 0.001). Taking an SUVmax value of 0.5 as that which would ensure greatest diagnostic accuracy, S and NPV were 100%, though percentage agreement did not increase (0.189; p < 0.001). PET discriminatory power was not affected by histological tumour subtype. Conclusions: The results of our study indicate that PET might be a useful test for examination of the mediastinum in lung cancer patients. Its high NPV suggests that the absence of mediastinal uptake could be used to proceed to surgical treatment without the need for further tests or examinations. Nevertheless, studies directly aimed to answer this specific question are needed.en
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshPredictive Value of Tests*
dc.subject.meshNeoplasm Staging*
dc.subject.meshLymphatic Metastasis*
dc.subject.meshHumans*
dc.subject.meshComparative Effectiveness Research*
dc.subject.meshSensitivity and Specificity*
dc.subject.meshMediastinum*
dc.subject.meshBiopsy*
dc.subject.meshTomography*
dc.subject.meshRetrospective Studies*
dc.subject.meshAged*
dc.subject.meshPatient Selection*
dc.titleUsefulness of Positron Emission Tomography in the Examination of Hilar and Mediastinal Lymphadenopathies in Patients with Suspicion of Lung Canceren
dc.typeJournal Articlees
dc.authorsophosPereiro-Brea, Tara;Golpe-Gómez, Antonio;Golpe-Sánchez, Antonio Miguel;Valdés, Luís;Martínez de Alegría, Anxo;Carreira-Villamor, José Martín;Ruano-Raviña, Alberto
dc.identifier.doi10.1155/2020/7909543
dc.identifier.pmid32587645
dc.identifier.sophos35845
dc.journal.titleCanadian Respiratory Journales
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de A Coruña - Complexo Hospitalario Universitario de A Coruña::Neumoloxíaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Neumoloxíaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Radiodiagnósticoes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS)es
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294363/pdf/CRJ2020-7909543.pdfes
dc.rights.accessRightsopenAccess
dc.subject.decsanciano*
dc.subject.decssensibilidad y especificidad*
dc.subject.decsestadificación de neoplasias*
dc.subject.decsestudios retrospectivos*
dc.subject.decspruebas de valores predictivos*
dc.subject.decsbiopsia*
dc.subject.decsselección de los pacientes*
dc.subject.decsmediastino*
dc.subject.decsmetástasis linfática*
dc.subject.decshumanos*
dc.subject.decsinvestigación comparativa de la efectividad*
dc.subject.decstomografía*
dc.subject.keywordCHUACes
dc.subject.keywordCHUSes
dc.subject.keywordIDISes
dc.typefidesArtículo Originales
dc.typesophosArtículo Originales
dc.volume.number2020.es


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