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dc.contributor.authorBatista, A. D.
dc.contributor.authorA Rodrigues, D.
dc.contributor.authorFigueiras Guzmán, Adolfo
dc.contributor.authorZapata-Cachafeiro, M.
dc.contributor.authorRoque, F.
dc.contributor.authorHerdeiro, M. T.
dc.date.accessioned2022-04-12T11:38:05Z
dc.date.available2022-04-12T11:38:05Z
dc.date.issued2020
dc.identifier.issn2079-6382
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/33171743es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/16464
dc.description.abstractAntibiotic resistance still remains a major global public health problem and the dispensing of antibiotics without a prescription at community pharmacies is an important driver of this. MEDLINE, Pubmed and EMBASE databases were used to search and identify studies reporting the dispensing of non-prescribed antibiotics in community pharmacies or drugstores that sell drugs for human use, by applying pharmacy interviews/questionnaires methods and/or simulated patient methods. Of the 4683 studies retrieved, 85 were included, of which 59 (69.4%) were published in low-and middle-income countries. Most of the papers (83.3%) presented a percentage of antibiotic dispensing without a prescription above 60.0%. Sixty-one studies evaluated the active substance and the most sold antibiotics without a prescription were amoxicillin (86.9%), azithromycin (39.3%), ciprofloxacin (39.3%), and amoxicillin-clavulanic acid (39.3%). Among the 65 articles referencing the diseases/symptoms, this practice was shown to be mostly associated with respiratory system problems (100.0%), diarrhea (40.0%), and Urinary Tract Infections (30.8%). In sum, antibiotics are frequently dispensed without a prescription in many countries and can thus have an important impact on the development of resistance at a global level. Our results indicate the high need to implement educational and/or regulatory/administrative strategies in most countries, aiming to reduce this practice.en
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleAntibiotic Dispensation without a Prescription Worldwide: A Systematic Reviewen
dc.typeJournal Articlees
dc.authorsophosBatista, A. D.;A Rodrigues, D.;Figueiras, A.;Zapata-Cachafeiro, M.;Roque, F.;Herdeiro, M. T.
dc.identifier.doi10.3390/antibiotics9110786
dc.identifier.pmid33171743
dc.identifier.sophos38931
dc.issue.number11es
dc.journal.titleAntibiotics (Basel, Switzerland)es
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS)es
dc.page.initial786es
dc.rights.accessRightsopenAccess
dc.subject.keywordIDISes
dc.typefidesArtículo de Revisiónes
dc.typesophosArtículo de Revisiónes
dc.volume.number9es


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