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dc.contributor.authorCamino Martinez, Tamara
dc.contributor.authorLago-Baameiro, Nerea
dc.contributor.authorMartís Sueiro, Aurelio Manuel
dc.contributor.authorCouto González, Iván 
dc.contributor.authorSANTOS BENITO, FRANCISCO FERNANDO 
dc.contributor.authorBaltar Boileve, Javier 
dc.contributor.authorPardo Pérez, María 
dc.date.accessioned2022-04-12T11:38:15Z
dc.date.available2022-04-12T11:38:15Z
dc.date.issued2020
dc.identifier.issn1661-6596
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/33316953es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/16468
dc.description.abstractThe extracellular vesicles (EVs) have emerged as key players in metabolic disorders rising as an alternative way of paracrine/endocrine communication. In particular, in relation to adipose tissue (AT) secreted EVs, the current knowledge about its composition and function is still very limited. Nevertheless, those vesicles have been lately suggested as key players in AT communication at local level, and also with other metabolic peripheral and central organs participating in physiological homoeostasis, and also contributing to the metabolic deregulation related to obesity, diabetes, and associated comorbidities. The aim of this review is to summarize the most relevant data around the EVs secreted by adipose tissue, and especially in the context of obesity, focusing in its protein cargo. The description of the most frequent proteins identified in EVs shed by AT and its components, including their changes under pathological status, will give the reader a whole picture about the membrane/antigens, and intracellular proteins known so far, in an attempt to elucidate functional roles, and also suggesting biomarkers and new paths of therapeutic action.en
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleDeciphering Adipose Tissue Extracellular Vesicles Protein Cargo and Its Role in Obesityen
dc.typeJournal Articlees
dc.authorsophosCamino, T.;Lago-Baameiro, N.;Martis-Sueiro, A.;Couto, I.;Santos, F.;Baltar, J.;Pardo, M.
dc.identifier.doi10.3390/ijms21249366
dc.identifier.pmid33316953
dc.identifier.sophos38955
dc.issue.number24es
dc.journal.titleINTERNATIONAL JOURNAL OF MOLECULAR SCIENCESes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Cirurxía plásticaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Cirurxía Xeral e dixestivaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS)es
dc.page.initial9366es
dc.page.final9366es
dc.rights.accessRightsopenAccess
dc.subject.decsanimales *
dc.subject.decsobesidad *
dc.subject.decshumanos *
dc.subject.decstejido adiposo *
dc.subject.decsproteoma *
dc.subject.keywordCHUSes
dc.subject.keywordIDISes
dc.typefidesArtículo Originales
dc.typesophosArtículo Originales
dc.volume.number21es


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