Mostrar el registro sencillo del ítem

dc.contributor.authorSantos Simoes, Ana Rita
dc.contributor.authorFernández Rozadilla, Ceres
dc.contributor.authorMaronas, O
dc.contributor.authorCarracedo Álvarez, Ángel
dc.date.accessioned2022-05-24T12:14:13Z
dc.date.available2022-05-24T12:14:13Z
dc.date.issued2020
dc.identifier.issn2075-4426
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/33228198es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/16832
dc.description.abstractIn recent decades, survival rates in colorectal cancer have improved greatly due to pharmacological treatment. However, many patients end up developing adverse drug reactions that can be severe or even life threatening, and that affect their quality of life. These remain a limitation, as they may force dose reduction or treatment discontinuation, diminishing treatment efficacy. From candidate gene approaches to genome-wide analysis, pharmacogenomic knowledge has advanced greatly, yet there is still huge and unexploited potential in the use of novel technologies such as next-generation sequencing strategies. This review summarises the road of colorectal cancer pharmacogenomics so far, presents considerations and directions to be taken for further works and discusses the path towards implementation into clinical practice.en
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleThe Road so Far in Colorectal Cancer Pharmacogenomics: Are We Closer to Individualised Treatment?en
dc.typeJournal Articlees
dc.authorsophosSimoes, AR Fernandez-Rozadilla, C Maronas, O Carracedo, A
dc.identifier.doi10.3390/jpm10040237
dc.identifier.pmid33228198
dc.identifier.sophos41938
dc.issue.number4es
dc.journal.titleJOURNAL OF PERSONALIZED MEDICINEes
dc.organizationServizo Galego de Saúde::Dirección Xeral de Asistencia Sanitaria::Fundación Pública Galega de Medicina Xenómicaes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS)es
dc.rights.accessRightsopenAccess
dc.subject.keywordFPGMXes
dc.subject.keywordIDISes
dc.typefidesArtículo de Revisiónes
dc.typesophosArtículo de Revisiónes
dc.volume.number10es


Ficheros en el ítem

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Atribución 4.0 Internacional
Excepto si se señala otra cosa, la licencia del ítem se describe como Atribución 4.0 Internacional